From ancient Egypt to early Greece, humans have long used pastes and scrubs to clean teeth, freshen breath and support a healthy mouth. While we’ve evolved beyond the toothpaste ingredients of crushed bones or burnt eggshells that our ancestors used (phew), we still rely on toothpaste for the same reasons. With all the options out there and all that they promise, it’s natural to wonder: Are all toothpastes the same? Does it really matter which one I use?